Sci. Adv. Today 2 (2016) 25236  
  Review Article  
Material advancements in bone-soft tissue fixation devices  
  Ajay Chhaya-Vijay Suryavanshi, Vivek Borse, Vaishali Pawar, Sindhu KR and Rohit Srivastava  
Department of Biosciences and Bioengineering, Indian Institute of Technology Bombay, Mumbai- 400076, Maharashtra, India
  Bone-soft tissue fixation devices are essential elements of orthopedic surgical toolkit. Such devices viz. screws, plates, pins, wires, rods, nails, etc. are extensively used in orthopedic practice for ameliorating musculo-skeletal anomalies like fractures, soft tissue fixations, arthrodeses, osteotomies, etc. There is an ever-rising demand of such bone repair appliances in world orthopedic market driven by the increasing aging demographics. Metals, ceramics, polymers, composites, etc. have been so far candidates for device materials, but, very few are able to match ideal properties of implant material, thus, there is still strong need and tremendous scope of improvement in the current materials. Orthopedic research field has seen paradigm shift in the development of biomaterials for orthopedic devices and is still experiencing constant amendments in order to improve upon functionalities, hence, performance. This review mainly focuses on following key points related to orthopedic devices: i) Brief introduction comprising of types, clinical indications, etc. ii) Market perspective in terms of statistics and market products, iii) biomaterials used iv) material advancements categorized into surface modifications and bulk modifications in terms of constituent filler and polymer matrix and v) future trends. In-depth understanding of biological and material engineering strategies will revolutionalize field of orthopedic biomaterial research to develop new generation of advanced orthopedic devices with desired clinical outcomes.  
  Cite this article as:  
  Ajay Chhaya-Vijay Suryavanshi, Vivek Borse, Vaishali Pawar, Sindhu KR and Rohit Srivastava, Material advancements in bone-soft tissue fixation devices, Sci. Adv. Today 2 (2016) 25236.