Sci. Adv. Today 2 (2016) 25259  
  Review Article  
   
   
         
Layer-by-layer assembly: Recent advances in designs and constructions of electrochemical sensors and biosensors  
  Junhui Xua,c, Yazhen Wanga, Shengshui Hub,c  
     
a Key Laboratory of Optoelectronic Chemical Materials and Devices, Ministry of Education, School of Chemical and Environmental Engineering, Jianghan University, Wuhan 430056, China
b College of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072, China
c Key Laboratory of Transducer Technology, Chinese Academy of Sciences, Beijing 10080, China

   
  Abstract  
  Layer-by-layer assembly has attracted tremendous interest in electroanalysis field since it provides a powerful and versatile way for modifying surfaces with desired architectures and properties. During the past several years, numerous electrochemical sensors with high sensitivity and selectivity have been developed by assembling various functional materials into the electrode interface via different operational approaches. This paper provides an overview of different strategies and principles involved in the layer-by-layer assembly for electrochemical sensing purpose, as well as recent advances in the construction and application of layer-by-layer based electrochemical sensors and biosensors. Finally, the remaining challenges and personal perspectives for future developments are also briefly discussed.  
     
   
  Cite this article as:  
  Junhui Xu, Yazhen Wang, Shengshui Hu, Layer-by-layer assembly: Recent advances in designs and constructions of electrochemical sensors and biosensors, Sci. Adv. Today 2 (2016) 25259.