Sci. Adv. Today 2 (2016) 25246  
  Review Article  
Composition and properties of the current in vivo electrochemical sensing  
  Yonggui Songa,b, Dan Sub and Li Wanga  
a Key Laboratory of Chemical Biology, Jiangxi Province, College of Chemistry and Chemical Engineering, Jiangxi Normal University, 99 Ziyang Road, Nanchang 330022, China
b Jiangxi University of Traditional Chinese Medicine, 56 Yangming Road, Nanchang 330006, China

  The continuously real-time online monitoring of biological compounds in vivo has long been a dream of mankind, with the development of electrochemical sensor technology and this dream is getting closer and closer to reality. In this review, the existing electrochemical detection methods in vivo are classified into two categories which are the microdialysis (MD)-electrochemical in vivo detection system and the micro-electrodes (ME)-electrochemical in vivo detection system. We summarize the current in vivo electrochemical detection methods and introduce the composition and characteristics of the sensors, and we discuss the advantages and disadvantages of each approach through the analysis of the electrode surface contamination resistance, continuous detection time, the number of simultaneously detected analytes, accuracy, selectivity and other properties. Finally, new perspectives and emerging technologies are discussed.  
  Cite this article as:  
  Yonggui Song, Dan Su and Li Wang, Composition and properties of the current in vivo electrochemical sensing, Sci. Adv. Today 2 (2016) 25246.