Sci. Adv. Today 2 (2016) 25247  
  Review Article  
Recent developments in pillar[5]arene chemistry  
  Raghuram R. Kothur and Peter J. Cragg  
School of Pharmacy and Biomolecular Sciences, Huxley Building, University of Brighton, Brighton BN2 4GK, UK
  The class of pillar[n]arene macrocycles has existed since 2008 when the synthesis and structure of the cyclopentamer, 1,4-dimethoxypillar[5]arene, was first reported. In subsequent years, members of the pillar[n]arene family have shown great potential in fields as diverse as polymer science, sensor technology and medical diagnostics. Over 350 papers have now been published on the pillar[n]arenes; this review focuses on advances made in the synthesis and applications of the pillar[5]arenes.  
  Cite this article as:  
  Raghuram R. Kothur and Peter J. Cragg, Recent developments in pillar[5]arene chemistry, Sci. Adv. Today 2 (2016) 25247.