Sci. Adv. Today 2 (2016) 25257  
  Review Article  
Supramolecular host-guest interactions: Modulations of chromophoric properties and prospects  
  Haridas Pal  
Radiation & Photochemistry Division, Bhabha Atomic Research Centre, Trombay, Mumbai - 400085, India
  In this review article an effort has been made to discuss the supramolecularly assisted modulations in the photophysical and prototropic (acid-base) properties of the organic chromophoric dyes on their interactions with macrocyclic host molecules, focusing on the possible applications of such systems in different applied areas. We have discussed in this article different aspects of the modulations mainly on the fluorescence properties and the prototropic equilibria of organic chromophoric dyes, caused by the host-guest inclusion complex formation of the dyes with macrocyclic cavitand molecules. These two important properties of the chromophoric dyes normally undergo large changes through host-guest inclusion complex formation and these changes can open up numerous possibilities of the concerned supramolecular systems for deployments in various applications like uses as sensors, utilizations in catalysis, developments of functional materials, constructions of organic electronic devices, developments of pharmaceuticals, deriving improved drug formulations, using in diagnosis, inventing methodologies for improved drug delivery, developments of nanomedicines, and many others. Since the subject of supramolecular chemistry is very vast, in this article we restrict our discussion mainly to the supramolecular host-guest systems involving the cyclodextrin (CD), calix[n]arene (CXn) and cucurbit[n]uril (CBn) classes of the macrocyclic hosts as the receptor molecules for the binding of the organic chromophoric dyes, that are realized to have enormous promises in regard to the uses in many of the aforesaid applied areas. Different examples of the CD, CXn and CBn based host-guest systems involving organic chromophoric dyes have been considered from the reported literatures, published by different research groups including ours, to made the discussion effective in highlighting the titled aspects of the present article. We believe that this review article will provide a basic understanding of the kind of modulations in the properties of the chromophoric dyes that take place through the formation of the inclusion complexes in the supramolecular dye-host systems and will help in visualizing how these modulations can be fruitfully deployed leading to different useful applications of such supramolecular systems for our benefits.  
  Cite this article as:  
  Haridas Pal, Supramolecular host-guest interactions: Modulations of chromophoric properties and prospects, Sci. Adv. Today 2 (2016) 25257.